pentobarbital will lower the level or effect of nicardipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
With therapeutic doses of TCAs, barbiturates raise metabolism and decrease blood concentrations of TCAs.
pentobarbital will decrease the level or outcome of fosamprenavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
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pentobarbital will lower the level or effect of ziprasidone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
Remark: Barbiturates may well enhance adverse effects, including respiratory despair, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and decrease blood concentrations of TCAs.
pentobarbital will minimize the extent or influence of iloperidone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will reduce the level or impact of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the level or influence of donepezil get more info by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
pentobarbital will lessen the level or outcome of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers may cut down partiaprevir and ritonavir stages, and thus lessened efficacy of Viekira Pak
The usage of barbiturates as sedatives within the postoperative surgical interval and as adjuncts to cancer chemotherapy is well founded
pentobarbital will decrease the extent or impact of hydrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or outcome of osilodrostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will reduce the extent or impact of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers could lead on to a minimize in fentanyl plasma concentrations, lack of efficacy or, perhaps, growth of a withdrawal syndrome within a individual who may have formulated Actual physical dependence to fentanyl.